For the last couple of seasons, I've been using a solution of milk and water to treat powdery mildew on my squash, zucchini, cucumbers and mellons. Here is Jacksonville Beach, FL, the cucurbits seem to very vulnerable to powdery mildew. We have seen powdery mildew on some of our cucurbits every season. We try to raise and maintain our gardens without using chemicals, so I sought out a more natural way to fight the powdery mildew. I stumbled upon some research that shows a milk solution is effective for fighting powdery mildew. I use a generic 32oz spray bottle (pictured above) to apply the milk solution. I add 1/4 cup of milk to the bottle then fill with water. I usually spray all the squash if any of them are infected. I try to wet the leaves on the top and bottom.
My experience has been, that if i catch the powdery mildew early, when the plants are still healthy but are showing white spots, treating them for 3 or 4 days in a row, usually clears up the mildew. When I start treating plants with milk after some of the leaves have withered and others leaves are yellowing or brown, the plants are less likely to survive, but some do. Early treatment, consistent over 3 or 4 days, seems to be the best solution for treating the powdery mildew.